Cardiovascular Cell Biology and Systems Medicine

Our group studies the cell biology of cardiovascular diseases. We utilize a human model system of induced pluripotent stem cells (iPSCs) in combination with site-specific genome editing, as well as biochemical and systems biology approaches.

Using these tools, we investigate the function of genetic variants in heart diseases, such as dilated and hypertrophic cardiomyopathy (DCM/HCM), which are leading causes of heart failure world-wide. Specifically, we are focusing on the interdependencies between mitochondrial function, metabolism and cellular homeostasis in cardiomyocytes and the cardiac vasculature.

Our goals are to recapitulate and rescue disease phenotypes in our human model of iPSC-derived cells, to understand molecular functions in cardiac health and disease, and to assess novel therapeutic directions, integrating systems medicine approaches


Group leader and CRC 1002 Project leader

Dr. rer. nat. Antje Ebert

Kontaktinformationen

Lab members

Cleophas Cheruiyot
M.Sc.
cleophas.cheruiyot(at)med.uni-goettingen.de
Phone: 0551-39-66309

Yuanyuan Dai
Ph.D. student
yuanyuan.dai(at)med.uni-goettingen.de
Phone: 0551-39-66309

Nadezda Ignatyeva
Ph.D. student
nadezda.ignatyeva(at)med.uni-goettingen.de
Phone: 0551-39-66309

Sinem Eylem Inal
B.Sc.
sinemeylem.inal(at)med.uni-goettingen.de
Phone: 0551-39-66309

Nosheen Saleem
Ph.D. student
hafizanosheen.saleem(at)med.uni-goettingen.de
Phone: 0551-39-66309

Ruheen Wali
B.Sc.
ruheen.wali(at)med.uni-goettingen.de
Phone: 0551-39-66309

Hang Xu
Ph.D. student
hang.xu(at)med.uni-goettingen.de
Phone: 0551-39-66309

Sergej Zeiter
BTA
sergej.zeiter(at)med.uni-goettingen.de
Phone: 0551-39-66309

Former lab members

Luca Avenali
Ph.D.

Tatiana Pochechueva 
Ph.D.

Shrivatsan Sampathkumar
M.Sc.

Ronald Siaden-Ortega
B.Sc.
 

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