Zelluläre Biophysik und Translationale Kardiologie
Cellular Biophysics and Translational Cardiology Section


A major focus of the Cellular Biophysics and Translational Cardiology Section are molecularly defined mechanisms and pathways, which control heart muscle function and underlie key pathophysiological changes associated with a variety of frequent and rare cardiovascular diseases. We use a broad spectrum of techniques including biophysical methods related to electrophysiology, cell biology with a focus on atrial and ventricular cardiomyocytes, molecular biology (e.g. cloning of expression plasmids and fusion proteins), high-resolution imaging (confocal and super-resolution STED microscopy), and transgenic models established by gene-editing strategies and analyzed by comprehensive phenotyping methods. Calcium-regulatory and calcium-regulated proteins are our central interest including Ryanodine Receptor (RyR) calcium release channels, Phospholamban, and Dysferlin, as well as their pathogenic mutations in humans. We also develop new classes of Multi-Targeted Drug Substances (MTDS) to mitigate dysregulated intracellular calcium signaling for example in the context of different forms heart failure and arrhythmia.
We are a founding member of the Excellence Cluster “Multi-scale Bioimaging – from Molecular Machines to Networks of Excitable Cells” (MBExC). Our campus-wide activities include, but are not limited to, the understanding of voltage-dependent calcium channel regulation through ion channel clustering, the role of different Ferlin proteins for vesicle fusion and membrane repair, and the development and application of innovative imaging techniques through interdisciplinary collaborations in academia and industry. We develop and apply a variety of advanced mass spectrometry workflows, for instance affinity proteomics and proximity proteomics, in close collaboration with the Service Unit Proteomics. The biomedical spectrum of available models includes human stem cells and bioengineered tissues, cardiac and neuronal tissues, and patient samples. Through the Hertha Sponer College and the Heart and Brain graduate school GRK 2428 we promote advanced support structures for M.Sc./Ph.D and cand. med. doctoral tracks, and scientific-to-biomedical exchange throughout academic career tracks.
For more information, please contact:
Prof. Dr. med. Stephan E. Lehnart, PD Dr. med. Sören Brandenburg, or Christiane Schulz
Our research group is located in the Heart Research Center Göttingen.
Vacancies
Please feel free to send in a speculative application at any time.

contact information
- e-mail address: slehnart(at)med.uni-goettingen.de
secretariat
- telephone: +49 551 3963631
- fax: +49 551 3963724
- e-mail address: cschulz(at)med.uni-goettingen.de
Mitarbeiter*innen
contact information
- telephone: +49 551 3963631
- fax: +49 551 3963724
- e-mail address: cschulz(at)med.uni-goettingen.de
Raum: 5 A2 32

contact information
- telephone: +49 551 3963643
- e-mail address: niklas.bader(at)med.uni-goettingen.de

contact information
- telephone: +49 551 3963643
- e-mail address: soeren.brandenburg(at)med.uni-goettingen.de
Facharzt für Innere Medizin
contact information
- telephone: +49 551 3963637
- e-mail address: brian.foo(at)med.uni-goettingen.de

contact information
- telephone: +49 551 3963640
- e-mail address: tobias.kohl(at)med.uni-goettingen.de
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- telephone: +49 551 3963642
- telephone: +49 551 3963643
- e-mail address: brigitte.korff(at)med.uni-goettingen.de

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- telephone: +49 551 3963637
- e-mail address: mufassra.mushtaq(at)med.uni-goettingen.de
contact information
- telephone: +49 551 3963643
- e-mail address: gabriel.riedemann(at)med.uni-goettingen.de
contact information
- telephone: +49 551 3963679
- e-mail address: tschulte(at)med.uni-goettingen.de

contact information
- telephone: +49 551 3964290
- e-mail address: anamaria.vergelleon(at)med.uni-goettingen.de

contact information
- telephone: +49 551 3963679
- e-mail address: sarah.zafar(at)med.uni-goettingen.de
Doktorand*innen

contact information
- telephone: +49 551 3963637
- e-mail address: carolin.fleischhacker(at)med.uni-goettingen.de
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- telephone: +49 551 3963637
- e-mail address: anastasiia.gorshkova(at)med.uni-goettingen.de
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- telephone: +49 551 3963637
- e-mail address: lorenz.liebmann(at)med.uni-goettingen.de

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- e-mail address: magnus.mathias(at)stud.uni-goettingen.de

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- e-mail address: justus.marks(at)stud.uni-goettingen.de
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- e-mail address: holmarne.meyer(at)med.uni-goettingen.de

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- e-mail address: kurt.mueller(at)med.uni-goettingen.de

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- telephone: +49 551 3963649
- e-mail address: marcel.rapoehn(at)stud.uni-goettingen.de

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- e-mail address: kim-chi.vu(at)med.uni-goettingen.de

contact information
- telephone: +49 551 3963645
- e-mail address: jasper.wedemeyer(at)med.uni-goettingen.de

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- telephone: +49 551 3963645
- e-mail address: justus.wegener(at)med.uni-goettingen.de

contact information
- telephone: +49 551 3963637
- e-mail address: yannik.zuehlke(at)med.uni-goettingen.de
Ehemalige Mitglieder
Gregory Antonios, Ph.D.
Research Scientist
Lina Paola Baena Lozada
Medical Laboratory Technician
Dana El Chami, Ph.D.
Ph.D. Student
Miroslav Dura, Ph.D.
Research Scientist
Verena Ebner
M.Sc. Student
Carolin Fleischhacker
med. Ph.D. Student
Sarah Gockel
med. Ph.D. Student
Konstantin Gusev, Ph.D.
Research Scientist
Kristian Hellenkamp, M.D.
Senior Physician, Ambulanz für fortgeschrittene Herzinsuffizienz
Jumana Jaber
Ph.D. Student
Alex Johnston
Ph.D. Student
Aruna Kalyanasundaram
Ph.D. Student
Daniel Kownatzki-Danger, Ph.D.
Research Scientist
Lorenz Liebmann
med. Ph.D. Student
Manuel Martinez-Lopez
Ph.D. student
Josefine Paulke
med. Ph.D Student
Jonas Peper
Ph.D. student
Tatiana Pochechueva, Ph.D.
Research Scientist
Arunraj Saranya Prakashrao Ph.D.
Research Scientist
Nour Raad, MD. Ph.D.
Resident
Rebecca R. Falk, Ph.D.
Research Scientist
Elisabeth Rebbein-Bode
Medical Laboratory Technician
Birgit Schumann
Medical Laboratory Technician
Niko Schwenzer
Ph.D. Student
Julia Hanni Steinbrecher, Dipl.-Biol.
General Electric (GE) Healthcare
Jan-Hendrik Streich, M.D.
Medical Advisor, Novartis Pharma GmbH
Dennis Uhlenkamp
Ph.D. student
Eva Wagner, Ph.D.
Research Scientist
Jörg Wegener, PD Dr.
Research Scientist
Silvio Weber, Ph.D.
Research Group Leader, TU Dresden / Christian-Albrechts-University of Kiel
Gunnar Weninger, Ph.D.
Research Scientist
Erdem Yilmaz
Ph.D. Student
Nina Zaremba
PhD Student