Zelluläre Biophysik und Translationale Kardiologie
Cellular Biophysics and Translational Cardiology Section
A major focus of the working group of Translational Cardiology are molecular mechanisms, which control muscle function and pathophysiological changes due to disease. We use a variety of techniques including biophysics, cell biology, molecular biology, high-resolution imaging (confocal and super resolution microscopy; voltage mapping), transgenic models and comprehensive phenotyping methods. In particular, calcium binding proteins and intracellular calcium signaling are a major interest. For example cardiac ryanodine receptor (RyR2) calcium release channels, which control cardiac contraction and relaxation and modulate physiological stress adaptation during the fight-or-flight response.
On the other hand, RyR2 channel dysfunction contributes to heart failure, arrhythmias, and sudden cardiac death. We develop therapeutic options for RyR2 mutation carriers with the syndrome Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT), characterized by stress-induced syncope and sudden death. Because RyR2 and other calcium binding proteins can directly contribute to cardiac and other disease forms, the molecular and cellular mechanisms are investigated. A large part of our research activities is "translational" by nature and contributes to increased understanding of the molecular basis of diseases like heart failure and sudden cardiac death. Additionally, novel diagnostic and therapeutic strategies are developed and tested.
Our research group is located in the Heart Research Center Göttingen.
Vacancies
Please feel free to send in a speculative application at any time.
Kontaktinformationen
- E-Mail-Adresse: slehnart(at)med.uni-goettingen.de
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- Telefon: +49 551 3963631
- Telefax: +49 551 3963724
- E-Mail-Adresse: cschulz(at)med.uni-goettingen.de
Mitarbeiter*innen
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- Telefon: +49 551 3963631
- Telefax: +49 551 3963724
- E-Mail-Adresse: cschulz(at)med.uni-goettingen.de
Raum: 5 A2 32
Kontaktinformationen
- Telefon: +49 551 3963643
- E-Mail-Adresse: soeren.brandenburg(at)med.uni-goettingen.de
Facharzt für Innere Medizin
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- Telefon: +49 551 3963637
- E-Mail-Adresse: brian.foo(at)med.uni-goettingen.de
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- Telefon: +49 551 3963640
- E-Mail-Adresse: tobias.kohl(at)med.uni-goettingen.de
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- E-Mail-Adresse: gabriel.riedemann(at)med.uni-goettingen.de
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- E-Mail-Adresse: tschulte(at)med.uni-goettingen.de
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- Telefon: +49 551 3963649
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- E-Mail-Adresse: birgit.schumann(at)med.uni-goettingen.de
Doktorand*innen
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- Telefon: +49 551 3963637
- E-Mail-Adresse: dana.elchami(at)med.uni-goettingen.de
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- E-Mail-Adresse: carolin.fleischhacker(at)med.uni-goettingen.de
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- E-Mail-Adresse: anastasiia.gorshkova(at)med.uni-goettingen.de
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- E-Mail-Adresse: jumana.jaber(at)med.uni-goettingen.de
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- E-Mail-Adresse: lorenz.liebmann(at)med.uni-goettingen.de
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- E-Mail-Adresse: manuel.martinezlopez(at)med.uni-goettingen.de
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- E-Mail-Adresse: marcel.rapoehn(at)stud.uni-goettingen.de
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- Telefon: +49 551 3963710
- E-Mail-Adresse: niko.schwenzer(at)med.uni-goettingen.de
Kontaktinformationen
- Telefon: +49 551 3963645
- E-Mail-Adresse: jasper.wedemeyer(at)med.uni-goettingen.de
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- E-Mail-Adresse: justus.wegener(at)med.uni-goettingen.de
Kontaktinformationen
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- E-Mail-Adresse: yannik.zuehlke(at)med.uni-goettingen.de
Ehemalige Mitglieder
Gregory Antonios, Ph.D.
Research Scientist
Miroslav Dura, Ph.D.
Research Scientist
Sarah Gockel
MD/PhD Student
Konstantin Gusev Ph.D.
E-Mail: kgusev(at)incras.ru
Institute of Cytology of the Russian Academy of Sciences
Dr. med. Kristian Hellenkamp
Oberarzt | Ambulanz für fortgeschrittene Herzinsuffizienz
Alex Johnston
PhD Student - IRTG 1816
Aruna Kalyanasundaram
PhD Student
Dr. Daniel Kownatzki-Danger
Research Scientist
Mufassra Mushtaq
PhD Student
Lina Paola Baena Lozada
Medical Laboratory Technician
Jonas Peper
Ph.D. student
Nour Raad, MD. Ph.D.
Resident
Dipl.-Biol. Julia Hanni Steinbrecher
General Electric (GE) Healthcare
Dr. Jan-Hendrik Streich
Medical Advisor, Novartis Pharma GmbH
Dennis Uhlenkamp
Ph.D. student
Dr. rer. nat. Eva Wagner
Research Scientist
PD Jörg Wegener
Research Scientist
Dr. rer. nat. Silvio Weber
Research Group Leader, TU Dresden, Christian-Albrechts-Universität zu Kiel
Dr. rer. nat. Gunnar Weninger
Research Scientist
Erdem Yilmaz
Ph.D. Student
Nina Zaremba
PhD Student