Zelluläre Biophysik und Translationale Kardiologie

Cellular Biophysics and Translational Cardiology Section

A major focus of the working group of Translational Cardiology are molecular mechanisms, which control muscle function and pathophysiological changes due to disease. We use a variety of techniques including biophysics, cell biology, molecular biology, high-resolution imaging (confocal and super resolution microscopy; voltage mapping), transgenic models and comprehensive phenotyping methods. In particular, calcium binding proteins and intracellular calcium signaling are a major interest. For example cardiac ryanodine receptor (RyR2) calcium release channels, which control cardiac contraction and relaxation and modulate physiological stress adaptation during the fight-or-flight response.

On the other hand, RyR2 channel dysfunction contributes to heart failure, arrhythmias, and sudden cardiac death. We develop therapeutic options for RyR2 mutation carriers with the syndrome Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT), characterized by stress-induced syncope and sudden death. Because RyR2 and other calcium binding proteins can directly contribute to cardiac and other disease forms, the molecular and cellular mechanisms are investigated. A large part of our research activities is "translational" by nature and contributes to increased understanding of the molecular basis of diseases like heart failure and sudden cardiac death. Additionally, novel diagnostic and therapeutic strategies are developed and tested.

Our research group is located in the Heart Research Center Göttingen.

Vacancies

Please feel free to send in a speculative application at any time.


Arbeitsgruppenleiter und SFB1002-Teilprojektleiter

Prof. Dr. Stephan E. Lehnart

Prof. Dr. Stephan E. Lehnart

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Sekretariat

Mitarbeiter*innen

Sekretariat Prof. Lehnart

Christiane Schulz

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  • Raum: 5 A2 32

Clinical and Research Fellow

Dr. Sören Brandenburg

Dr. Sören Brandenburg

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Research Scientist

Brian Foo

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Associated Research Scientist

Dr. rer. nat. Tobias Kohl

Dr. rer. nat. Tobias Kohl

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Medical Laboratory Technician

Brigitte Korff

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Research Scientist

Tatiana Pochechueva

 Tatiana Pochechueva

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Research Scientist

Arunraj Saranya Prakashrao

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Medical Laboratory Technician

Elisabeth Rehbein-Bode

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Medical Laboratory Technician

Timo Schulte

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Medical Laboratory Technician

Birgit Schumann

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Research Scientist

PD Dr. Jörg Wegener

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Doktorand*innen

PhD Student

Dana El Chami

 Dana El Chami

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med. PhD Student

Carolin Fleischhacker

 Carolin Fleischhacker

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PhD Student

Jumana Jaber

 Jumana Jaber

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PhD Student

Aruna Kalyanasundaram

 Aruna Kalyanasundaram

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PhD Student

Manuel Martinez-Lopez

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PhD Student

Mufassra Mushtaq

 Mufassra Mushtaq

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med. PhD Student

Nora Josefine Paulke

 Nora Josefine Paulke

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med.dent. PhD Student

Marcel Rappöhn

 Marcel Rappöhn

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PhD Student

Niko Schwenzer

 Niko Schwenzer

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PhD Student

Nina Zaremba

 Nina Zaremba

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med. PhD Student

Yannik Zühlke

 Yannik Zühlke

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Ehemalige Mitglieder

Gregory Antonios, Ph.D.
Research Scientist

Miroslav Dura, Ph.D.
Research Scientist

Sarah Gockel
MD/PhD Student

Konstantin Gusev Ph.D.
E-Mail: kgusev(at)incras.ru
Institute of Cytology of the Russian Academy of Sciences

Dr. med. Kristian Hellenkamp 
Oberarzt | Ambulanz für fortgeschrittene Herzinsuffizienz

Alex Johnston
PhD Student - IRTG 1816

Dr. Daniel Kownatzki-Danger
Research Scientist

Lina Paola Baena Lozada 
Medical Laboratory Technician

Jonas Peper
Ph.D. student

Nour Raad, MD. Ph.D.
Resident

Dipl.-Biol. Julia Hanni Steinbrecher
General Electric (GE) Healthcare

Dr. Jan-Hendrik Streich
Medical Advisor, Novartis Pharma GmbH

Dennis Uhlenkamp
Ph.D. student

Dr. rer. nat. Eva Wagner
Research Scientist

Dr. rer. nat. Silvio Weber
Research Group Leader, TU Dresden, Christian-Albrechts-Universität zu Kiel 

Dr. rer. nat. Gunnar Weninger
Research Scientist

Erdem Yilmaz
Ph.D. Student

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